Urologic Surgery Research

For enrollment information involving the following trials, please contact a member of our research support staff.

Perioperative Physical Activity (Pedometer)

Frailty Study

Ketorolac

CAUTI Microbiome


Perioperative Physical Activity (Pedometer)

Prospective Randomized Study of Exercise in Patients Undergoing Urologic Surgery

Inclusion Criteria:

  • Adult patients scheduled for operative procedure with an inpatient postoperative stay

  • Willing and able to give blood samples, complete a questionnaire, fill out the step log, and return to clinic for 1st post-operative appointment

Exclusion Criteria:

  • None

Treatment:

Patients are given a pedometer and asked to record their daily steps in a log. The purpose of this study is to determine if pedometers can aid in increasing patients' physical activity during the perioperative period.

Principal Investigators: Kenneth Ogan, MD; Viraj Master, MD, PhD; John Pattaras, MD


Frailty Study

Frailty as a Predictor of Outcomes in Surgical Patients

Inclusion Criteria:

  • Patients already scheduled for major surgery requiring an overnight hospital stay that are willing to do the study’s preoperative assessment tools

  • Patients must be able to give informed consent and be 18 years and older

Exclusion Criteria:

  • Patients diagnosed with severe dementia, Parkinson’s disease, or other functional motor disorders

  • Patients diagnosed with a stroke and who have residual motor and/or cognitive deficits

  • Patients taking carbidopa/levodopa, donepezil hydrochloride, or antidepressant medications

Principal Investigators: Kenneth Ogan, MD; Viraj Master, MD, PhD

Co-Investigators & Collaborators: John Pattaras, MD, and three surgeons from the Department of Surgery: John Sweeney, MD; David Kooby, MD; Shishir Maithel, MD


Ketorolac

Pilot Study of Biomarker Evaluation and Safety of Pre-Incisional Ketorolac for Patients Undergoing Surgical Resection for Non-Small Cell Lung Cancer and Renal Cell Carcinoma

Inclusion Criteria:

  • Pathology-proven or suspected stage 1 or 2 NSCL and Stage 3 T3N0 RCC that require surgical resection as the treatment of choice

  • ECOG performance status (PS) 0, 1, or 2

  • Age ≥ 18 years and ≤80 years

Exclusion Criteria:

  • Individuals with pure lung ground-glass opacity (GGO) lesions or mixed GGO with <50% solid component

  • Patients undergoing pneumonectomy

  • History of cancer in the three years prior to surgery (except for basal-cell carcinoma of the skin or cervical neoplasia)

  • Contraindication for NSAIDs (peptic ulcer disease, pre-operative chronic kidney disease with eGFR <60 measured with the MDRD equation used widely, including at Emory>, allergies or intolerance to NSAIDs, coagulation disorder, or age > 80 years)

  • Having taken an NSAID within five days prior to surgery

  • Immunocompromised status

  • Refusal or inability to understand the protocol and consent form or to receive follow-up in line with the recommendations

  • Preoperative hemoglobin < 9.0

Principal Investigator: Viraj Master, MD, PhD

Co-Investigators & Collaborators: Onkar Khullar, MD (Department of Surgery); Haydn Kissick, PhD; Manoj Bhasin, PhD, MS (Department of Pediatrics and Department of Biomedical Informatics); Yuan Liu, PhD, MS (Department of Bioinformatics)


CAUTI Microbiome

Urinary Microbiome in Catheter Associated Urinary Tract Infections

Inclusion Criteria:

  • 18 years of age

  • Chronic catheter > 12 months

Exclusion Criteria:

  • Calculus disease

  • Genitourinary anatomic abnormality or prior reconstruction procedure

  • Immunosuppressed

  • Current or chronic antibiotic treatment

Principal Investigator: Brendan Browne, MD