Models for Predicting PCa Progression (MPPP)
Under the direction of Dr. Leland W. K. Chung, molecular understanding of the urologic disease process and therapeutic targeting are featured in this program. Leaders of five areas of research emphasis are identified:
- Mechanisms of tumor-stroma interaction (Leland W. K. Chung, Ph.D.)
- Lipid and extracellular matrix-mediated cell signaling (Magnus Edlund, Ph.D.)
- Developmental mechanisms stromal-epithelial interaction (Ruoxiang Wang. M.D., Ph.D.)
- Steroid receptor axis in cancer progression (Haiyen E. Zhau, Ph.D.)
Opportunities are provided to students and trainees to participate in
interactive research collaborations among the above described research
programs in the following areas:
- Extracellular matrix integrin signaling in cancer progression
- Molecular targeting at antiangiogenic and transcription factor pathways for cancer metastasis
- Development of novel imaging animal models for the study of cancer growth and metastasis
- Novel genes involved in normal development, cell transformation and neoplastic progression
- Androgen receptor axis in hormone refractory prostate cancer
For more information, please contact the investigator by email or call (404) 778-4319.